PROTEINS : Structure, Function, and Bioinformatics publishes original reports of significant experimental and analytic research in all areas of protein research: structure, function, computation, genetics, and design. The journal encourages reports that present new experimental or computational approaches for interpreting and understanding data from biophysical chemistry, structural studies of proteins and macromolecular assemblies, alterations of protein structure and function engineered through techniques of molecular biology and genetics, functional analyses under physiologic conditions, as well as the interactions of proteins with receptors, nucleic acids, or other specific ligands or substrates. Research in protein and peptide biochemistry directed toward synthesizing or characterizing molecules that simulate aspects of the activity of proteins, or that act as inhibitors of protein function, is also within the scope of PROTEINS. In addition to full-length reports, short communications (usually not more than 4 printed pages) and prediction reports are welcome. Reviews are typically by invitation; authors are encouraged to submit proposed topics for consideration.

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PROTEOMICS is the premier international source for information on all aspects of applications and technologies in proteomics. It provides the most comprehensive coverage in the field, spanning significant technical developments in all major gel and non-gel based proteomic platforms and their application in every area of life sciences. Papers describing novel applications of proteomics are especially welcome. Topics include whole proteome analysis of any organism, expression profiling, disease studies, pharmaceutical, agricultural and biotechnological applications, and analysis of cellular systems, organelles and protein complexes.

The scope of the journal, reflected in its title, is purposefully broad. It will be open to contributions that describe the structural and functional properties of proteins and their expression, particularly with respect to developmental time courses. Emphasis will be placed on determining how the presence or absence of proteins affect biological responses, and how the interaction of proteins with germane cellular partners allows them to function. Thus, the focus clearly will be on both structural and functional aspects of proteins. However,as noted, technological advances have an important role in a field that is still being developed and significant advances in methodology will be deemed to be appropriate subject matter too.

The Protein Journal (formerly the Journal of Protein Chemistry) publishes original research work on all aspects of protein investigations. These include studies concerned with covalent or three-dimensional structure, assembly, genetics, evolution, proteomics, molecular biology, engineering, and peptide synthesis. The contents include the application of research to the elucidation and interpretation of the molecular bases of the biological activity of proteins.

PROTEOMICS - Clinical Applications has developed into a key source of information in the field of applying proteomics to the study of human disease and translation to the clinic. With 12 issues per year, the journal will publish papers in all relevant areas including:

• basic proteomic research designed to further understand the molecular mechanisms underlying dysfunction in human disease
• the results of proteomic studies dedicated to the discovery and validation of diagnostic and prognostic disease biomarkers
• the use of proteomics for the discovery of novel drug targets
• the application of proteomics in the drug development pipeline
• the use of proteomics as a component of clinical trials.

The Journal of Proteome Research (JPR) provides content encompassing all aspects of global protein analysis and function, emphasizing the synergy between physical and life sciences resulting in a multidisciplinary approach to the understanding of biological processes.

JPR publishes original peer-reviewed research Articles, Letters, Reviews, Perspectives, Communications and Technical Notes. In addition, the journal provides Research Profiles about papers published in the journal; Meeting News from proteomics meetings; Government and Society News for the proteomics community; Proteomics Projects, updated progress on large proteomics endeavors; a Calendar of upcoming proteomics conferences and meetings; and Online News about current research published outside of the journal, bioinformatics tools, and other data resources.

Proteome Science is an Open Access, peer-reviewed, online journal considering research in proteomics. The journal is specifically interested in manuscripts that integrate functional or structural proteomic analysis with cell or developmental biology.

Proteome Science will consider studies in the area of structural biology, mass spectrometry, protein arrays, bioinformatics, HTS assays, protein chemistry, cell biology, signal transduction and physiology - as long as a component of the study relates to proteomics.

Protein Science, the flagship journal of The Protein Society, serves an international forum for publishing original reports on all scientific aspects of protein molecules. The Journal publishes papers by leading scientists from all over the world that report on advances in the understanding of proteins in the broadest sense. Protein Science aims to unify this field by cutting across established disciplinary lines and focusing on “protein-centered” science.

The Journal encompasses the structure, function, and biochemical significance of proteins, their role in molecular and cell biology, genetics, and evolution, and their regulation and mechanisms of action. Topics of particular interest include, but are not limited to:

• Structure of proteins and strategies of determining protein structure by chemical, biophysical, and recombinant methods
• Peptides
• Protein domains
• Protein folding and molecular dynamics
• Novel isolation procedures
• Enzyme action and regulation
• Interactions of proteins with nucleic acids, lipids, ligands, and other proteins
• Receptor-mediated signal transduction and other trans-membrane phenomena
• The functions of proteins in replication, supramolecular assembly, immune reactions, development, and other biological processes
• Protein trafficking, synthesis and sorting
• Recognition, localization and signaling of proteins

The Journal of Proteomics covers all areas of applied and basic research in Proteomics using multi-disciplinary approaches to unravel biological processes. Emphasis is placed on translational research and biomarker discovery in human, animal, micro-organism and plant systems. The journal provides a forum for activities in proteomics and helps strengthen the links between research scientists all over the world.

In addition to original papers, the journal welcomes state-of-the-art reviews and update papers, letters to the editor, book reviews, reports and news, as well as Proceedings of EuPA national congresses. The journal also publishes the official EuPA guidelines papers.

Briefings in Functional Genomics is an international forum reviewing the use, development and exploitation of functional genomic approaches in all areas of biological research. The journal provides a centralised resource for researchers in the field of functional genomics as well as guidance to scientists new to the area.

Subjects covered by BFG include but are not restricted to: the identification and functional characterisation of coding and non-coding features in genomes, microarray technologies, gene expression profiling, next generation sequencing, pharmacogenomics, phenomics, SNP technologies, transgenic systems, mutation screens and genotyping. Articles range in scope and depth from the introductory level to specific details of protocols and analyses, encompassing bacterial, fungal, plant, animal and human data.

As molecular medicine moves beyond genomics to proteomics, the goal becomes the characterization of the cellular circuitry and the understanding of the impact of disease and therapy on cellular networks. Clinical Proteomics provides a scholarly forum for novel scientific research in the field of translational proteomics. The journal places special emphasis on the application of proteomic technology to all aspects of clinical research. A key feature is its commitment to rapid scientific review and timely publication of submitted manuscripts. Coverage includes: Clinical sample collection and handling to preserve proteins; New technology, including protein arrays, mass spectroscopy, microanalytic devices, nanotechnology, and biosensors for protein-based clinical bioassays and clinical chemistry assays; Bioinformatics tools including pattern recognition, artificial intelligence, and computer learning algorithms.

Expert Review of Proteomics (ISSN 1478-9450) seeks to collect together technologies, methods and discoveries from the field of proteomics to advance scientific understanding of the many varied roles protein expression plays in human health and disease.

The journal adopts the unique Expert Review article format, offering a complete overview of current thinking in a key technology area, research or clinical practice, augmented by the following sections:

Expert commentary - a personal commentary on the most effective or promising strategies
Five-year view - a clear perspective of future prospects within a realistic timescale
Key issues - an executive summary cutting to the author's most critical points

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